Iwai North America
What is Laminin?

Laminins are cell adhesion proteins Basement membrane component Heterotrimer composed of α, β, and γ chains At least 12 isoforms in human Interacts with cell surface receptors, integrins Promotes cell survival and regulates cellular behaviors (migration and polarization) and fate (differentiation) Combination of laminins and cell types in vivo Biological functions of laminins are exerted […]

iMatrix-111 Cell Matrices

iMatrix-111 Maintenance and purification of HPCs, Hepatocytes and Nerve cells. Buy Online Product Basics iMatrix-111 is a highly purified recombinant human Laminin 111-E8 fragment expressed by CHO-S cell. Laminin 111 is known to be present in the liver and binds to integrin α7X2β1 and α6β1. Laminin 111 is essential for the formation of the three […]

iMatrix 332
iMatrix-332 Cell Matrices

iMatrix 332 Maintenance and purification of corneal epithelial cells and keratinocytes. Buy Online Product Basics iMatrix-332 is a recombinant human Laminin 332-E8 fragments protein expressed by CHO-S cell. Laminin 332 is composed of α3β2γ2 chain, which is known to bind to integrin α3β1 and α6β4. It is essential for cells in the epithelial basement membranes, […]

iMatrix-221 Cell Matrices

iMatrix 221 Maintenance and purification of cardiomyocytes and skeletal muscles Buy Online Product Basics iMatrix-221 is highly purified human Laminin 221-E8 fragments recombinantly expressed by CHO-S cell. Laminin-221 E8 fragment protein is known to bind to Intergin α7X2β1 of the cell surface, making an ideal matrix for the differentiation and maintenance of cardiomyocytes and skeletal […]

iMatrix-411 Cell Matrices

iMatrix 411 Induction of vascular endothelial cells from human PSCs Buy Online Product Basics iMatrix-411 is a recombinant Laminin-411 E8 fragment protein used as a cell culture matrix. Laminin-411 is a predominant isoform found in the basal membrane of the endothelial cells in capillary vessels, and it mainly binds to the cell surface transmembrane receptors […]

iMatrix-511& Silk Cell Matrices

iMatrix 511 Series Maintenance and expansion of pluripotent stem cells (PSCs) & mesenchymal stem cells (MSCs) Buy Online iMatrix-511 iMatrix-511 Silk Easy iMatrix-511 Product Basics The iMatrix-511 is an innovative cell culture matrix that is compatible with a wide variety of cell types. It is exceptionally well-suited for pluripotent and mesenchymal stem cells. This product […]