Laminins are cell adhesion proteins
- Basement membrane component
- Heterotrimer composed of α, β, and γ chains
- At least 12 isoforms in human
- Interacts with cell surface receptors, integrins
- Promotes cell survival and regulates cellular behaviors (migration and polarization) and fate (differentiation)
Combination of laminins and cell types in vivo
- Biological functions of laminins are exerted depending on the α chain
- Laminin isoforms are diversity during in cell differentiation process
By choosing proper laminin isoforms,
pluripotent stem cells differentiate efficiently into target cells
Recombinant Laminin Products - iMatrix series
iMatrix-511 is for maintenance and expansion of puripotent stem cell (PSCs).
iMatrix-511 Silk is cost-efficient alternative of iMatrix-511.
