It is a long established fact that a reader of a page when looking at its layout.

    iMatrix 221

    Maintenance and purification of cardiomyocytes and skeletal muscles

    Product Basics

    iMatrix-221 is highly purified human Laminin 221-E8 fragments recombinantly expressed by CHO-S cell. Laminin-221 E8 fragment protein is known to bind to Intergin α7X2β1 of the cell surface, making an ideal matrix for the differentiation and maintenance of cardiomyocytes and skeletal muscles.

    Key Features

    Technical Information

    Differentiated cardiomyocytes pulsating on iMatrix-221

    Specification

    • Format: Liquid Solution (175 ug/vial @0.5 mg/mL), Solvent: PBS (-)
    • Storage temperature: 2-15 °C
    • Manufactured by: Nippi, Inc. 1-1-1 Senju-Midoricho, Adachi-ku, Tokyo, Japan

    Pricing

    iMatrix-221

    • SKU: N-892013
    • Price: $80.00
    • Incl. US shipping fee
    • * Only one purchase per lab *

    350ug size (175ug x 2 tubes)

    • SKU: N-892061
    • Price: $435.00

    1050ug size (175ug x 6 tubes)

    • SKU: N-892062
    • Price: $1,165.00

    References & Literature

    1. Nishiuchi, R., Takagi, J., Hayashi, M., Ido, H., Yagi, Y., Sanzen N., Tsuji T., Yamada M., & Sekiguchi K. (2006). Ligand-binding specificities of laminin-binding integrins: A comprehensive survey of laminin–integrin interactions using recombinant α3β1, α6β1, α7β1 and α6β4 integrins. Matrix Biology, 25(3), 189-197. https://doi.org/10.1016/j.matbio.2005.12.001

    2. Taniguchi, Y., Ido, H., Sanzen, N., Sato-Nishiuchi, R., Futaki, S., & Sekiguchi, K. (2009). The C-terminal Region of Laminin β Chains Modulates the Integrin Binding Affinities of Laminins. The Journal of Biological Chemistry, 284(12), 7820-31. https://doi.org/10.1074/jbc.M809332200

    3. Israeli-Rosenberg, S., Manso, A. M., Okada, H., & Ross, R. (2014). Integrins and Integrin-Associated Proteins in the Cardiac Myocyte. Circular Research, 114(3), 572-586. https://doi.org/10.1161/CIRCRESAHA.114.301275

    4. Method for producing cardiomyocyte population from pluripotent stem cells. Patent Publication No. WO2016043168 A1. 2017-6-22

    FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES